Vardenafil

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Description

171599-83-0 Sex Steroid Vardenafil For Male Enhancer 

Product Name:  Vardenafil
CAS: 224785-91-5
MF: C23H33ClN6O4S
MW: 525.06
Assay: 99%
Appearance: White or almost white crystalline powder, odorless, a little acerbity
Product Categories: Steroid
Anabolic steroid Raw Powder Vardenafil hydrochloride
Solubility: soluble in alcohol and water.
Usage: It is pharmaceutical raw material, for the treatment of erectile dysfunction
Storage: keep dry place, avoid strong light and heat

What is vardenafil, and how does it work ?

Vardenafil is an oral drug that is used to treat impotence, the inability to attain or maintain a penile erection. It has a mechanism of action that is similar to sildenafil (Viagra), and tadalafil (Cialis). Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase in size and increase the delivery of blood to the penis. At the same time, the blood vessels carrying blood away from the penis decrease in size and decrease the removal of blood from the penis. Sexual stimulation that leads to the engorgement and erection causes the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase to produce cyclic guanosine monophosphate (cGMP). The cGMP is primarily responsible for increasing and decreasing the size of the blood vessels carrying blood to and from the penis, respectively. Vardenafil prevents an enzyme called phosphodiesterase-5 (PDE-5) from destroying cGMP so that cGMP persists longer. The longer cGMP persists, the more prolonged the engorgement of the penis. Vardenafil was approved by the FDA in August 2003.

What is the dosage for vardenafil?

For most individuals, the recommended dose of vardenafil regular tablets is 10 mg per day taken 60 minutes before intercourse. If there is no response or side effects, the dose may be increased to 20 mg or, if there are side effects, it may be reduced to 5 mg.

Individuals 65 years of age or older should begin therapy with 5 mg.Individuals who are taking medications that increase the blood levels of vardenafil should start treatment with 2.5 to 5 mg of vardenafil. (See drug interactions.)

Orally disintegrating tablets (ODT) are not interchangeable with regular vardenafil tablets because they are better absorbed and produce higher blood levels than regular tablets. The recommended dosing when using ODT is one tablet 60 minutes before intercourse. Only one tablet should be used per day. It should be placed on the tongue until it disintegrates and should not be swallowed with water.

CERTIFICATE OF ANALYSIS

Product Name Vardenafil Batch No 20160216
Quantity 20kgs Made Date 2016.02.16
Report Date 2016.02.17 Exp Date 2019.02.16
Test Items Specification Test Results
Description White or almost white crystalline powder White crystalline powder
Melting Point 191.0~193.0℃ 192℃
Loss of drying ≤1.0% 0.5%
Heavy Metal ≤20ppm 15ppm
TLC Only one spot Only one spot
Assay ≥99.5% 99.91%
Conclusion It complies with the enterprise standard