Proviron is Schering’s (now Bayer’s) brand name for the oral androgen mesterolone (1-methyl dihydrotestosterone). Similar to dihydrotestosterone, mesterolone is a strong androgen with only a weak level of anabolic activity. This is due to the fact that like dihydrotestosterone, mesterolone is rapidly reduced to inactive diol metabolites in muscle tissue where concentrations of the 3-hydroxysteroid dehydrogenase enzyme are high. The belief that the weak anabolic nature of this compound indicates a tendency to block the androgen receptor in muscle tissue, thereby reducing the gains of other more potent muscle-building steroids, should likewise not be taken seriously. In fact, due to its extremely high affinity for plasma binding proteins such as SHBG, mesterolone may actually work to potentate the activity of other steroids by displacing a higher percentage into a free, unbound state. Among athletes, mesterolone is primarily used to increase androgen levels when dieting or preparing for a contest, and as an anti-estrogen due to its intrinsic ability to antagonize the aromatase enzyme.
Proviron is helpful in stacks because of its unique ability to keep the body from turning testosterone into estrogen, thus giving the testosterone a better anabolic effect. Also, Proviron can help boost the potency of testosterone in the body by freeing testosterone from its binding to sex hormone-binding globulin (SHBG).
Product name: Proviron Mesterolone Powder
Assay: 99% min.
Appearance: White crystalline powder.
The drug has shown value in treating men with mental health issues, such as depression,sexual dysfunction, impotency and low libido, anxiety and bipolar disorders. The drug also is commonly used to treat sexual dysfunction, including low sperm count. Additionally, mesterolone may enhance the effectiveness of other steroids. Mesterolone binds to estrogen receptors, reducing their activity, which not only reduces estrogen production, but also encourages natural testosterone production in the body.
Another benefit of proviron is that it binds very well to SHBG (sex hormone binding globulin), which is the hormone responsible for reducing free testosterone circulating in the body. This is probably the reason why some use proviron during PCT.In addition, it’s a precursor to full TRT (testosterone replacement therapy).