Growth hormone (HGH) is a protein secreted by adenohypophysis cells and is a peptide hormone. The growth hormone produced by recombinant DNA technology is referred to as r-HGH. Under normal circumstances, growth hormone HGH was pulsed secretion, growth hormone (hGH) secretion by the hypothalamus produced by the growth hormone releasing hormone (GHRH) and growth hormone inhibition hormone (GHIH, also known as somatostatin SS) regulation, also By sex, age and circadian rhythm of the impact of sleep secretion significantly increased. The main physiological function of growth hormone is to promote the growth of all other tissues outside the nerve tissue; promote the body’s metabolism and protein synthesis; promote lipolysis; antagonize the role of insulin; inhibit the use of glucose to make blood sugar and so on. Serum growth hormone determination contributes to the diagnosis of growth hormone deficiency caused by giant disease, acromegaly and hereditary growth hormone deficiency.